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Year 2026/27
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Learning Activity - Copy of Copy of 09 T-Cell Mediated Immunity
TypeLecture
ModuleLINMED - Copy of Lincoln Medicine 1 (Copy of Copy of 09 Blood and Immunity)
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TR100 - Copy of Training
Year
Year 2026/2027
Duration (mins)
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Compare and contrast the antigen receptors of T cells and B cells.

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Define the functional roles of helper and cytotoxic T cells.

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Explain the nature of antigen peptide recognition by T cells and the role of antigen presenting cells (APCs).

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Describe HLA class I and HLA class II molecules as peptide binding and presenting proteins.

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Explain the interactions of CD8 T cells with HLA class I and CD4 T cells with HLA class II.

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Outline the different antigen processing pathways that generate peptides that are presented by either HLA class I or HLA class II proteins.

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Explain why helper T cells mainly express CD4 and are HLA class IIrestricted, whereas cytotoxic T cells mainly express CD8 and are HLA class Irestricted.

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Describe the role of dendritic cells in capturing and processing antigens, and stimulating T cell activation.
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