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Year 2026/27
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Learning Activity - Copy of Copy of 07 Regulation of Gene Expression
TypeLecture
ModuleLINMED - Copy of Lincoln Medicine 1 (Copy of Copy of 07 Genes and Early Embryology)
Programme
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TR100 - Copy of Training
Year
Year 2026/2027
Duration (mins)
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Copy of Copy of

Recount and, where appropriate, describe the stages of eukaryotic gene expression and where regulation can occur.

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Understand the importance of transcriptional control to the overall control of gene expression.

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Know that transcriptional control includes two core mechanisms and what these are.

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Briefly discuss features of eukaryotic transcription factors.

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Understand the concept of DNA looping and transcription factors acting at a distance from the promoter of a gene.

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Describe the role of histones to higher order DNA structures.

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Describe the concepts of transcriptional co-activators and co-repressors and give general examples of such.

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Understand how histone modification can both activate or repress transcription.

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Understand how extracellular signals can link to changes in gene expression.

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Give examples of transcription factors that control cell fate decisions and/or are implicated in human disease.

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Describe the different ways that post-transcriptional RNA processing can provide additional regulatory complexity.

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Cite an example that integrates the many aspects of gene expression control.
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