Curriculum Mapping System
Learning Activity - Copy of Copy of 09 Helper T-Cells and Cytokines
TypeLecture
ModuleLINMED - Copy of Lincoln Medicine 1 (Copy of Copy of 09 Blood and Immunity)
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Outline the main types of cytokines and their properties.

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Distinguish the derivation and properties of Th1 and Th2 cell.

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Describe the interactions between antigen presenting cells and helper T cells, and between helper T cells and antigenspecific B cells, that lead to antibody production. Outline the anatomical locations of these interactions, and the processes of B cell maturation that occur in germinal centres.

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Explain how activated, antigenspecific lymphocytes home to sites of infection and inflammation.

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Explain how Th2 cells can promote mast cell and eosinophil activation.

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Explain how Th1 cells promote macrophage activation, and how this can lead to granulomatous inflammation in chronic mycobacterial infections, for example.

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Outline the main immunological features of tuberculosis and leprosy, and how the nature of the T cell response determines the clinical spectrum of leprosy.

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