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| Programme | SoLS - Life Sciences Modules Database (Level 4) C741 - B.Sc. Hons. Biochemistry and Molecular Medicine (Part 2 - Restricted Group 2) C742 - M.Sci. Hons. Biochemistry and Molecular Medicine (Part 2 - Restricted Group 2) C721 - M.Sci. Hons. Biochemistry and Biological Chemistry (Part 3 - Restricted Group 1) C703 - M.Sci. Hons. Biochemistry (Part 2 - Alternative Group 1) C700 - B.Sc. Hons. Biochemistry (Part 2 - Alternative Group 1) C703 - M.Sci. Hons. Biochemistry (Part 3 - Restricted) C742 - M.Sci. Hons. Biochemistry and Molecular Medicine (Part 3 - Restricted) |
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| Year |  Select a new weight:
           https://curriculum.nottingham.ac.uk/2026/view/tree/91335/year_lookup/XXIDXX
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| Accrediting Bodies | https://curriculum.nottingham.ac.uk/2026/view/tree/91335/year_lookup/XXIDXX
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| Module Code | LIFE4114 |
| Credits | 20 |
Level: Level 4
Target Students: Available to all students registered for C700, C703, C741, C742, C720, C721. Available to JYA/Erasmus students.
Taught Semesters:
| Semester | Assessment |
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| Autumn | Assessed by end of Autumn Semester |
Prerequisites: None.
Corequisites: None.
Summary of Content: This module covers some of the more modern ideas surrounding tumourigenesis and tumour progression. The first part of the course will cover our current understanding of the molecular basis of tumour progression. Following lectures will focus both on research into the fundamentals of cancer biology and the biochemical basis for the treatment of patients with cancer. The following features will be included: 1. The role of oncogenes and tumour suppressor genes in normal and tumour cells. 2. Multistep tumourigenesis and the hallmarks of cancer 3. Cancer cell invasion and metastasis 4. Genome instability 5. Cancer stem cells 6. The tumour microenvironment 7. Cancer research 8. Cancer therapy
Method and Frequency of Class:
| Activity | Number Of Weeks | Number of sessions | Duration of a session |
|---|---|---|---|
| Lecture | 11 weeks | 2 per week | 1 hour |
| Workshop | 1 weeks | 1 per week | 3 hours |
Activities may take place every teaching week of the Semester or only in specified weeks. It is usually specified above if an activity only takes place in some weeks of a Semester
Method of Assessment:
| Assessment Type | Weight | Requirements |
|---|---|---|
| Exam 1 | 70 | Essay style exam |
| Presentation 1 | 30 | 15 minute student presentation |
Convenor:
Dr M Georgiou
Education Aims: The aim of this course is to expand the student’s knowledge of how cancer cells form, how they metastasise and explain and discuss how cancer research is undertaken and current approaches to cancer treatments.
- Sessions
- Learning Activities
- Outcomes
- Other Modules
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Students will understand the nature and function of oncogenes and tumour supressor genes in normal and cancer cells |
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Students will understand multistep tumourigenesis and the hallmarks of cancer |
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Students will understand the role of stem cells in cancer formation |
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Students will understand the role of genome instability in tumour progression |
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Students will understand the importance of the tumour microenvironment |
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Students will understand how cancer is modelled in in vivo systems, to better understand disease mechanisms |
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Students will understand present day cancer chemotherapy including drug actions and problems |
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Students will understand the search for new cancer therapies using current knowledge of cancer cell biology |
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Student will develop their ability to use of the library |
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Student will develop their ability to use search engines to review relevant current literature |
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Student will develop their presentation and communication skills. |
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