The module will focus on the synthesis of a variety of natural (and unnatural) compounds of relevance to biology and medicine, with particular reference to the goals and achievements of contemporary organic synthesis as illustrated by a range of case studies. There will be particular emphasis on the use of modern synthetic methodology to address problems such as chemoselectivity, regiocontrol, stereoselectivity, atom economy and sustainability. The module will focus on the application of new methodology for the rapid, efficient and highly selective construction of a range of target compounds, particularly those that display significant biological activity (e.g. anticancer compounds). The module will also address how a greater understanding of mechanism is important in modern organic chemistry.

1. To provide an appreciation and understanding of contemporary organic synthesis with focus on the design and implementation of strategies for the synthesis of compounds that are important in biology and medicine. 2. To compare and contrast different synthetic strategies and tactics for the assembly of complex molecules. 3. To establish a thorough grounding in the use of modern synthetic methodology, including transition-metal and organocatalysis, and asymmetric synthesis. 4. To emphasise the importance of mechanistic understanding of organic reactions.