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Learning Activity - Enzymes: kinetics, inhibition and regulation
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ModuleLIFE1029 - Genes, Molecules and Cells
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Understand the theory of enzyme catalysis

Understand the factors that affect an enzyme reaction (temperature, pH and substrate concentration)

Understand the concept of the Km of an enzyme and its relevance

Understand the concept of the Vmax of an enzyme and its relevance

Understand the concept of the Kcat of an enzyme and its relevance

Know the difference between reversible and irreversible enzyme inhbitors

Be able to explain how sarin gas is an irreversible inhibitor of acetylcholine esterase

Be able to distinguish between competitive, noncompetitive and uncompetitive enzyme inhibition

Be able to explain the properties of an allosteric enzyme

Understand the concerted and sequential models of enzyme allostery

Understand the principle of enzyme regulation through covalent modification

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